Controversies and progresses in prophylactic cranial irradiation for small cell lung cancer
10.3760/cma.j.issn.1004-4221.2018.01.024
- VernacularTitle:SCLC脑预防照射——争议中的进展
- Author:
Han SUN
1
;
Lujun ZHAO
Author Information
1. 300060,天津医科大学肿瘤医院放疗科国家肿瘤临床医学研究中心 天津市"肿瘤防治"重点实验室 天津市恶性肿瘤临床医学研究中心
- Keywords:
Carcinoma,small cell lung/prophylactic cranial irradiation;
Progress
- From:
Chinese Journal of Radiation Oncology
2018;27(1):112-115
- CountryChina
- Language:Chinese
-
Abstract:
Small cell lung cancer (SCLC) is a kind of highly invasive malignant neoplasm, which is characterized by short survival and high-risk cranial metastasis. Therefore, application of prophylactic cranial irradiation(PCI) is of clinical significance to reduce the incidence of brain metastasis and prolong the patients' survival on the basis of radio-and chemo-therapy. Nevertheless, the indications and clinical value of PCI have been controversial in recent years. These controversies mainly include the significance of PCI for extensive-stage SCLC,the indications of PCI for limited-stage SCLC and the alternative approaches for PCI. In this paper, the controversies and progresses of PCI applied in clinical practice are investigated and reviewed.
