Research progress on the association between c-Met and radiosensitivity in esophageal cancer
10.3760/cma.j.issn.0254-5098.2017.12.016
- VernacularTitle:c-Met与食管癌放疗敏感性的相关性研究进展
- Author:
Chenxue JIANG
1
;
Feiying GU
;
Yaping XU
Author Information
1. 浙江省肿瘤医院放疗科
- Keywords:
Esophageal cancer;
c-Met;
Radiosensitivity;
Target therapy
- From:
Chinese Journal of Radiological Medicine and Protection
2017;37(12):962-964
- CountryChina
- Language:Chinese
-
Abstract:
Esophageal cancer is a common gastrointestinal cancer in China with poor prognosis.Radiotherapy is the main treatment of esophageal cancer,and radiosensitivity of the tumor cell is a significant reason for the efficacy of radiotherapy.Mesenchymal-epithelial transition factor (c-Met) and its signaling pathway play an significant role in tumorigenesis,development,invasion,metastasis and treatment resistance.This review summarizes the association between expression of c-Met and radiosensitivity in esophageal cancer.