A Case of Macrophage Activation Syndrome Developed in Female Adolescent with Systemic Lupus Erythematosus.

Author: Seung Woo KEUM ¹ ; Min Jae KIM ; E Young BAE ; Seung Beom HAN ; Nack Gyun CHUNG ; Dae Chul JEONG ; Jin Han KANG
Author Information

1. Department of Pediatrics, College of Medicine, The Catholic University of Korea, Seoul, Korea. dcjeong@catholic.ac.kr
Publication Type:Case Report
Keywords: Macrophage activation syndrome; Systemic lupus erythematosus; Adolescent
MeSH: Adolescent*; Autoimmune Diseases; Diagnosis; Etoposide; Female; Fever; Humans; Lupus Erythematosus, Systemic*; Macrophage Activation Syndrome*
From:Journal of Rheumatic Diseases 2014;21(2):96-100
CountryRepublic of Korea
Language:Korean
Abstract: Macrophage activation syndrome (MAS) is a severe complication in patients with autoimmune disease. We should consider MAS in patients with autoimmune disease, who present with newly developed fever, and MAS needs proper management due to grave outcome. We report a case of MAS in a 15-year-old adolescent girl, who was newly diagnosed with systemic lupus erythematosus 1 month before the diagnosis of MAS. Her MAS was improved by intensive treatment, including etoposide.