Chemical constituents from Gentianella acuta
10.3969/j.issn.1001-1528.2017.12.021
- VernacularTitle:尖叶假龙胆化学成分的研究
- Author:
xue Hai KUANG
1
;
Bin WANG
;
qian Qian WU
;
song Gao WU
;
Ying YU
;
jun Ya CHEN
;
hong Qiu WANG
;
you Bing YANG
;
bin Zhi WANG
Author Information
1. 黑龙江中医药大学
- Keywords:
Gentianella acuta (Michx.) Hulten;
chemical constituents;
isolation and identification
- From:
Chinese Traditional Patent Medicine
2017;39(12):2546-2550
- CountryChina
- Language:Chinese
-
Abstract:
AIM To study the chemical constituents from Gentianella acuta (Michx.) Hulten.METHODS The 30％ and 90％ ethanol fractions of 70％ ethanol extract from G.acuta were isolated and purified by silica,ODS and preparative HPLC column,then the structures of obtained compounds were identified by spectral data.RESULTS Nine compounds were isolated and identified as sinenoside Ⅰ (1),(+)-lariciresinol-4,4'-0-bis-β-D-glucopyranoside (2),(+)-8-hydroxylariciresinol-4'-O-β-D-glucopyranoside (3),(+)-lariciresinol-4-O-3-D-glucopyranoside (4),(7S,8R)-erythro-7,9,9'-trihydroxy-3,3'-dimethoxy-8-O-4'-neolignan-4-O-β-D-glucopyranoside (5),(7S,8R)-erythro-4,9,9'-trihydroxy-3,3'-dimethoxy-8-O-4'-neolignan-7-O-β-D-glucopyranoside (6),(7S,8R)-erythro-4,7,9-trihydroxy-3,3'-dimethoxy-8-O-4'-neolignan-9'-O-β-D-glucopyranoside (7),balanophonin (8),urolignoside (9).CONCLUSION Compounds 2-9 are isolated from genus Gentianella for the first time.
