Pulmonary high-resolution CT and radionuclide pulmonary perfusion/ventilation scan in pediatric patients with bronchiolitis obliterans
10.3760/cma.j.issn.2095-2848.2017.12.003
- VernacularTitle:儿童闭塞性细支气管炎的肺高分辨率CT与核素肺灌注/通气显像
- Author:
Wei WANG
1
;
Tong YU
;
Guoshuang FENG
;
Yueqin TIAN
;
Kunling SHEN
Author Information
1. 100045,首都医科大学附属北京儿童医院呼吸感染中心
- Keywords:
Bronchiolitis obliterans;
Child;
Tomography,X-ray computed;
Radionuclide imaging;
Technetium Tc 99m aggregated albumin;
Technetium Tc 99m pentetate
- From:
Chinese Journal of Nuclear Medicine and Molecular Imaging
2017;37(12):763-766
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the clinical application of pulmonary high-resolution CT (HRCT) and radionuclide pulmonary V/Q scan in pediatric patients with bronchiolitis obliterans (BO).Methods From February 2005 to April 2011,30 BO pediatric patients (18 males,12 females,age range:7 months-14 years) in Beijing Children's Hospital Affiliated to Capital Medical University were recruited for pulmonary HRCT and radionuclide pulmonary V/Q scan.Kappa test was used to describe the consistency between "Mosaic perfusion pattern" in pulmonary HRCT and radionuclide pulmonary ventilation abnormalities.Results "Mosaic perfusion patterns" in pulmonary HRCT were showed in 30 cases (100%).Ventilation defects were found in 27 cases (90.0%) and perfusion defects in 25 cases (83.3%).The Kappa value between "Mosaic perfusion pattern" in pulmonary HRCT and pulmonary ventilation defects was 0.201 (0.1340.268),which was slightly higher than that between "Mosaic perfusion pattern" in pulmonary HRCT and pulmonary perfusion defects (0.147 (0.061-0.233)),but there was no statistical difference.Conclusions " Mosaic perfusion pattern" in pulmonary HRCT cannot distinguish between pulmonary ventilation and perfusion abnormalities.V/Q scan could be a useful tool for BO.