Application of improved regional citrate anticoagulation in child hemofiltration
10.3969/j.issn.1671-8348.2017.30.008
- VernacularTitle:改良局部枸橼酸抗凝在儿童血液滤过的应用
- Author:
Ke BAI
1
;
Hongxing DANG
;
Yueqiang FU
;
Fang ZHOU
;
Chenjun LIU
Author Information
1. 重庆医科大学附属儿童医院重症医学科/儿童发育疾病研究教育部重点实验室/儿科学重庆市重点实验室/重庆市儿童发育重大疾病诊治与预防国际科技合作基地 400014
- Keywords:
hemofiltration;
child;
anticoagulants;
renal replacement therapy;
regional citrate anticoagulation
- From:
Chongqing Medicine
2017;46(30):4200-4203
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the application of citrate injected by dialysis pump in regional citrate anticoagulation (RCA) for child continuous hemofiltration(CHF). Methods The clinical data of 49 children patients with RCA-CHF with citrate anticoagulation in ICU of the Affiliated Children's Hospital of Chongqing Medical University from September 2015 to January 2017 were retrospectively analyzed. All cases were divided into the traditional group(20 cases) for conducting RCA-CHF treatment and improved group(29 cases,dialysis pump injection of citric acid) for conducting RCA-CHF under CHF mode. The occurence situation of common complications such as infusion pump bubble alarming, blood undesirable collection, bleeding and coagulation, and complications such as filter lifetime and citrate anticoagulation were observed. Results The bubble alarming and filter lifetime had statistical difference between the two groups(P<0.05). The biochemical indicators before and after treatment, and Na+ , iCa2+ , TCa2+/iCa2+ and HCO3- before and after treatment had statistical difference between the two groups. But Na+ , iCa2+ , TCa2+ /iCa2+and HCO3- before and after treatment had no statistical difference between the improved group and traditional group(P>0.05). Conclusion The improved technology of dialysis pumps instead of citrate pumps can more safely and more effectively use in child RCA-CHF treatment.
