Research progress of 14-3-3 protein and lipid metabolism
10.3760/cma.j.issn.1000-6699.2017.12.019
- VernacularTitle:14-3-3蛋白与脂代谢的研究进展
- Author:
Mengdan LIU
1
;
Chaoyu ZHU
;
Li WEI
Author Information
1. 200233,上海交通大学附属第六人民医院内分泌代谢科
- Keywords:
14-3-3 protein;
Lipid metabolism
- From:
Chinese Journal of Endocrinology and Metabolism
2017;33(12):1093-1096
- CountryChina
- Language:Chinese
-
Abstract:
Tyrosine-3-monooxy genase/tryptophane-5-monooxy-genase activator protein ( 14-3-3 protein ) is a family of highly conservative and widely expressed acidic polypeptides in all eukaryotic cells. The 14-3-3 protein family consists of adaptors and scaffolds that participates in many cellular processes, such as apoptosis and metabolism. Recent studies have found that 14-3-3 protein is associated with many proteins related to lipid metabolism. It could be exploited for therapy of lipid metabolism disorders. This paper briefly describes the role of the 14-3-3 protein in the lipid metabolism and its related diseases.
