Protective effect and its molecular mechanism of dexmedetomidine on nerve injury
10.3760/cma.j.issn.1673-4904.2018.01.021
- VernacularTitle:右美托咪定在神经损伤中的保护作用及分子机制
- Author:
Yangyang SHAN
1
;
Hao WANG
;
Hongtao LIU
Author Information
1. 中国医科大学附属盛京医院麻醉科
- Keywords:
Dexmedetomidine;
Cognition disorders;
Review
- From:
Chinese Journal of Postgraduates of Medicine
2018;41(1):74-77
- CountryChina
- Language:Chinese
-
Abstract:
Dexmedetomidine (DEX) is a specific α2 receptor agonist, which has high analgesic and neuroprotective effects on the basis of less side effects.Due to the advantages of DEX,it is currently used in ICU,anesthesia and other fields.In recent years,its neuroprotective effect has attracted extensive attention.It has been reported that DEX plays a critical role in the injured development brain, postoperative cognitive dysfunction (POCD) and other diseases.The specific mechanism is unknown, which needs to be further explored.
