Therapeutic effect of subtotal parathyroidectomy for 72 uremic patients with secondary hyperparathyroidism
10.3969/j.issn.1009-9905.2017.09.004
- VernacularTitle:72例继发性甲状旁腺功能亢进行甲状旁腺次全切除术的治疗分析
- Author:
yuan Heng GAO
1
;
Nan XU
;
peng Xun LUO
;
jie Xin LIU
;
xian Dong ZHOU
;
cheng Pei MAI
;
ying Gui ZHANG
Author Information
1. 暨南大学附属第二医院(深圳市人民医院)甲状腺外科 广东 深圳 518020
- Keywords:
Secondary hyperparathyroidism;
Subtotal Parathyroidectomy;
Parathyroid hormone;
Remic
- From:
Chinese Journal of Current Advances in General Surgery
2017;20(9):684-686,691
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To retrospectively analyze the therapeutic effect of subtotal parathyroidectomy (sT-PTX) on uremic patients with secondary hyperparathyroidism (SHPT).Methods:Seventy two SHPT patients treated with sT-PTX in our hospital were enrolled in this study.Serum parathyroid hormone(PTH),calcium(Ca) and phosphorus(P) obtained in the preoperative,postoperative and followup periods were collected and compared.Their symptoms,postoperative complications and relapse were recorded.Results:(1)sT-PTX operation performed successfully in 70/72 patients(97.2％).(2)After sT-PTX,bone pain and itching improved rapidly,with the improvement of nutritional status,Partial patients with renal hypertension were remitted compared with preoperative.Thirteen cases can walk without wheelchair after sT-PTX.(3)Serum PTH,Ca,and P decreased significantly after sT-PTX for one week,one month and 6 months as compared with those before sT-PTX(P＜0.05).(4)Postoperative hypocalcemia was frequently seen(53/72,53.6％) but could be effectively controlled by intravenous calcium infusion.(5)SHPT recurred in the 6 months after sT-PTX in 4 cases (5.7％).Conclusions:T-PTX can effectively decrease PTH level and improve symptoms,and is a safe measure for the treatment of uremic patients with SHPT.
