Recent progress of researches on brain development in children with congenital heart disease
10.3760/cma.j.issn.1001-4497.2017.12.018
- VernacularTitle:先心病脑发育研究进展
- Author:
Bowen SHI
1
;
Zhongqun ZHU
Author Information
1. 200127,上海交通大学医学院附属上海儿童医学中心心胸外科
- From:
Chinese Journal of Thoracic and Cardiovascular Surgery
2017;33(12):760-763
- CountryChina
- Language:Chinese
-
Abstract:
While the early mortality and complication rate of the congenital heart disease were significantly reduced, the long-term complications, especially the neurological complications, have become more and more concerning. Periopeartive nerve injury was used to be mainly attributed to cardiopulmonary bypass, however, with improvement of surgical and cardiopulmonary bypass technology, this has become significantly lower. For many years efforts to reduce nervous system damage by improving the cardiopulmonary bypass perfusion method has yielded little results. In recent years, it is found that during preoperative period, even as early as fetal period, children with congenital heart disease show slow brain development and damage, which was considered to be more important than extracorporeal circulation in determining long-term nervous system development. Thus recognition of preoperative brain malfunction in children with congenital heart disease has important clinical significance. This paper reviews the recentresearch and progress in this area.
