Acute necrotizing encephalopathy
10.3760/cma.j.issn.2095-428X.2017.24.003
- VernacularTitle:急性坏死性脑病
- Author:
Ruifeng JIN
1
Author Information
1. 山东大学齐鲁儿童医院神经内科
- Keywords:
Acute necrotizing encephalopathy;
Diagnosis;
Treatment
- From:
Chinese Journal of Applied Clinical Pediatrics
2017;32(24):1848-1853
- CountryChina
- Language:Chinese
-
Abstract:
Acute necrotizing encephalopathy (ANE)is a rare type of acute encephalopathy which occurs secondary to virus infection. Individuals who suffer from ANE usually have an exaggerated immune response to various viral infections. The pathologic change is focal vascular injury which leads to destruction of the blood - brain barrier and vascular permeability that cause brain edema,petechial hemorrhage,and necrosis. The imageological changes of ANE have diagnostic significance which show multifocal,symmetric brain lesions including bilateral thalamus 100% invol-ving. Intravenous glucocorticoids,immunoglobulin,and plasmapheresis should be effective for treatment.