Correlation of heart-type fatty acid-binding protein and glycogen phosphorylase enzyme BB in brain with septic myocardial injury
10.3760/cma.j.issn.1673-4912.2017.12.015
- VernacularTitle:心脏型脂肪酸结合蛋白及糖原磷酸化酶同工酶脑型与脓毒症心肌损伤的相关性研究进展
- Author:
Ke PENG
1
Author Information
1. 中国医科大学附属盛京医院小儿重症监护室
- Keywords:
Sepsis;
Myocardial injury;
Cardiac markers;
Heart-type fatty acid binding protein;
Brain glycogen phosphorylase isoenzyme type
- From:
Chinese Pediatric Emergency Medicine
2017;24(12):939-943
- CountryChina
- Language:Chinese
-
Abstract:
The incidence of sepsis is on the rise, and the mortality is also high. Myocardial injury caused by sepsis is one of the important causes of death. However,there is no clear and unified diagnostic criteria to sepsis complicated with myocardial injury. The clinical diagnostic criteria of myocardial injury is mainly based on cardiac ultrasound,myocardial markers and so on. But the measurement of ejection fraction is needed to consider the impact of preload and afterload of left ventricula,also the subjective level of opera-tors. So cardiac markers play an important role in the detection of myocardial injury in sepsis and can reflect the severity of myocardial injury and sepsis,especially in the early diagnosis and prognosis. Heart-type fatty acid binding protein and brain glycogen phosphorylase isoenzyme type exhibit higher sensitivity, specificity and stability compared to other traditional cardiac markers in the clinical diagnosis of myocardial injury, which are worth to be studied and applied in the clinical diagnosis of myocardial injury.
