Comparative study on the interictal electrophysiological characteristics of symptomatic temporal lobe epilepsy and extratemporal lobe epilepsy patients
- VernacularTitle:症状性颞叶癫痫与颞叶外癫痫患者发作间期电生理特征的对比研究
- Author:
Bin ZHANG
1
;
lian Gui ZHANG
Author Information
1. 718000,陕西省榆林市第一医院神经内科
- Keywords:
temporal lobe epilepsy;
extratemporal lobe epilepsy;
electrophysiology;
interictal epileptiform discharges
- From:
Journal of Clinical Neurology
2017;30(6):431-434
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the characteristics and some related influences of interictal epileptiform discharges (IEDs) for symptomatic temporal lobe epilepsy(TLE) and extratemporal lobe epilepsy(ETLE) patients in whom with focal lesion on structural imaging .Methods The electrophysiological and clinical data of 257 epilepsy patients were retrospectively analyzed , all of whom had a focal lesion revealed by structural imaging .Patients were divided into 2 groups according to the locaton of the lesion:TLE group and ETLE group , patients were also divided into 3 subgroups according to the relationship between the location of IEDs and the lesion :TLE-1/ETLE-1 subgroup with a norm interictal EEG; TLE-2/ETLE-2 subgroup with IEDs absolutely located in brain lobes in which lesion located;TLE-3/ETLE-3 subgroup with IEDs exceed or absolutely not located in the lobes in which lesion located . Results The proportion of TLE-1 was significantly lower than ETLE-1 ( P<0.01 ) , while the proportion of TLE-2 was significantly higher than ETLE-2(P<0.01).The proportion of the TLE-3 subgroup increased along with a longer duration, and the proportion of ETLE-3 subgroup decreased along with a lower seizure frequency , and also the older the age at onset .Conclusions The positive rate of IEDs and its positioning accuracy are significantly higher in symptomatic TLE than that in ETLE patients .The distribution of IEDs is more likely to be affected by epilepsy duration in TLE , while it is more easily to be affected by seizure frequency and age at onset in ETLE .
