Application of MALDI-TOF MS in detection of bacterial resistance mechanisms

VernacularTitle:基质辅助激光解吸电离飞行时间质谱在细菌耐药机制检测中的应用进展
Author: Lina FENG ¹ ; Congrong LI ; Xuan CAI ; Shupeng JIANG
Author Information

1. 430060,武汉大学人民医院检验科
Keywords: Bacteria; Resistance mechanisms; MALDI-TOF MS
From: Chinese Journal of Clinical Infectious Diseases 2017;10(6):467-472
CountryChina
Language:Chinese
Abstract: Bacterial resistance has become a serious problem that the whole world is facing.Routine bacterial drug resistance testing methods such as K-B test and dilution method are time-consuming and incapable to identify the specific drug resistance mechanism , which can not meet the needs of clinicians. MALDI-TOF MS overcomes the shortcomings of traditional methods and has broad application prospects in detection of bacterial resistance and drug resistance mechanism.This article reviews the recent progress on the application of MALDI-TOF MS in detection of bacterial drug resistance mechanisms.