The clinical application of postoperative early enteral immunonutrition in totally endoscopic esophagectomy
10.16151/j.1007-810x.2016.05.009
- VernacularTitle:术后早期肠内免疫营养在全腔镜食管癌根治术中的临床应用
- Author:
zhao Yan XU
1
;
Zhen ZHANG
;
Qiang GUO
;
feng Yue ZHANG
;
wang Shi WEN
;
hua Zhen LI
;
bo Ming WANG
;
qiang Zi TIAN
Author Information
1. 河北医科大学第四医院胸五科
- Keywords:
Thoracoscopy;
Laparoscopy;
Esophagectomy;
Enteral Immunonutrition
- From:
Parenteral & Enteral Nutrition
2017;24(6):355-360
- CountryChina
- Language:Chinese
-
Abstract:
Objective:TTo evaluate the nutritional status,immune function and clinical effectiveness of early enteral immunonutrition in patients receiving totally endoscopic esophagectomy.Methods:There were 90 patients receiving totally endoscopic esophagectomy enrolled in Department of Thoracic Surgery of The Fourth Hospital of Hebei Medical University between May 2015 and October 2016.The patients were randomly divided into three groups,enteral immunonutrition group (EIN group,n =30),common enteral nutrition group(EN group,n =30)and parenteral nutrition group (PN group,n =30).The levels of nutritional indexes,immune indexes,C-reactive protein (CRP) were measured preoperation and 1day,3days,7days after surgery.We also observed the first postoperative anal exhaust time,infectious complications and the length of hospital stay.Results:There were no significant differences in age,gender,tumor location,clinical stage,CRP,the nutritional indexes and immune indexes between the three groups before operation.On the first day after operation,the nutritional indexes and immune indexes of the three groups were significantly lower than those before operation,then all the indexes began to recover.Otherwise,CRP of the three groups were significantly higher than those before operation,then fell down in the following days,the rate of EIN group and EN group was faster than that of PN group on the day 3 after surgery and the EIN group was the fastest on the day 7 after surgery.There were significant differences in the first postoperative anal exhaust time,pneumonia and the length of hospital stay.And there was no significant difference in the incidence of anastomotic fistula between the three groups(x 2=1.071,P =0.585).Conclusions:Postoperative early enteral immunonutrition can improve the nutritional status and the immune response,promote the rapid recovery in the patients receiving totally endoscopic esophagectomy.
