Thermal tissue effects of the second-generation argon plasma coagulation on human stomach tissue :An ex vivo study
10.7652/jdyxb201801018
- VernacularTitle:第二代氩离子凝固疗法对人离体胃组织的热组织学效应
- Author:
Li ZHANG
1
;
Lei DONG
;
Jia LIU
;
ming Yi LI
;
yang Shi MA
;
cang Bai ZOU
Author Information
1. 西安交通大学医学院第二附属医院消化科
- Keywords:
argon plasma coagulation;
ablation technique;
digestive system endoscopy;
histological effect
- From:
Journal of Xi'an Jiaotong University(Medical Sciences)
2018;39(1):84-87,92
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the thermal effects of the second-generation argon plasma coagulation (VIO APC/APC2) on ex vivo human stomach tissue with different mode ,output power and application time .Methods The thermal effects of VIO APC were studied on fresh surgery-resected human stomach tissues .Different output powers were combined with mode "forced (F )","pulse , effect 1 (P1 )" and "pulse , effect 2 (P2 )";three application time ,the depth and maximum diameter of each injury were recorded .Results The depth of tissue injuries was correlated with output power (P<0 .001) ,energy (P=0 .008) and mode (P=0 .013) .The maximum diameter of injuries was correlated with output power (P<0 .001) ,application duration (P=0 .001) ,energy (P<0 .001) and mode (P=0 .001) .The incidence of harmful damage was only related to mode (P=0 .012) .The depth of tissue injuries was P1> F> P2 (P<0 .05) ,and the maximum diameter of injuries was P2> P1> F (P<0 .05) . Conclusion Different modes of VIO APC can create different thermal effects on the gastric tissues .Compared with F mode ,P1 mode creates deeper injuries while P2 mode creates larger but shallow injuries .All the three modes may cause injuries involving muscularis propria .
