Effects of different bolus and swallow patterns on esophageal manometry in patients with gastroesophageal reflux disease
10.7652/jdyxb201801019
- VernacularTitle:不同食团和吞咽方式对胃食管反流病患者食管测压结果的影响
- Author:
Yan YIN
1
;
yu Xiao XU
;
Yan ZHAO
;
yang Xiao REN
;
fang Gui LU
;
ni Xiao YAN
;
Lei DONG
;
xiang Shui HE
Author Information
1. 西安交通大学第一附属医院消化内科
- Keywords:
high resolution manometry;
solid swallow;
continuous swallow;
manometric parameter;
ineffec-tive esophageal motility
- From:
Journal of Xi'an Jiaotong University(Medical Sciences)
2018;39(1):88-92
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of different bolus and swallow patterns on esophageal manometry in patients with gastroesophageal reflux disease by high resolution manometry .Methods Patients with gastroesophageal reflux disease questionnaire score of more than 8 points and positive 24-hour pH monitoring were included in the study .All the patients were detected by liquid swallow ,solid swallow and continuous swallow .The parameters and comprehensive diagnosis were in accordance with the Chicago Standard .Results A total of 42 patients with gastroesophageal reflux disease were enrolled . Compared with the dynamic parameters of liquid swallow ,the residual pressure of upper esophageal sphincter [(11 .07 ± 3 .97 ,5 .29 ± 3 .36)mmHg] decreased ,the distal latency [(6 .28 ± 1 .87 ,8 .98 ± 2 .25)s] ,and lower esophageal sphincter relaxation time [(7 .79 ± 0 .98 ,10 .69 ± 13 .04)s] prolonged significantly (all P<0 .05) .In the comprehensive diagnosis of esophageal motility ,compared with liquid swallow (38 .1% ) , continuous liquid swallow showed a more sensitive positive diagnostic rate of ineffective esophageal motility (IEM) (63 .2% ) ,with a significant difference (P=0 .008) .Compared with that of liquid swallow ,the diagnostic rate (45 .2% ) of IEM by the solid swallow did not differ significantly (P=0 .581) . Among the ineffective contraction ,the rate of failed contraction (44.3% ) of solid swallow was higher than that of liquid swallow (22 .6% ) .Conclusion Solid swallow is more likely to induce severe esophageal hypomotility disorders than liquid swallow.Continuous swallow has more sensitivity in the diagnosis of IEM.Therefore.it can be used as a supplement to routine manometry in patients with eastroesophageal reflux disease.
