Correlation Analysis between Morning Blood Pressure Surge and Coronary Microvascular dysfunction
10.3969/j.issn.1006-5725.2017.24.017
- VernacularTitle:高血压晨峰现象与冠状动脉微循环的相关性
- Author:
Jianyu ZHANG
1
;
Qian LIANG
;
Zhaoyan XU
;
Jian LI
;
Jinming CEN
;
Baiqiang MEI
;
Xili YANG
Author Information
1. 528000,广东省佛山市第一人民医院心内科
- Keywords:
morning blooding peak surge;
hypertension;
index of microcirculatory resistance;
multi-ple linear regression analysis
- From:
The Journal of Practical Medicine
2017;33(24):4090-4093
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the correlation between morning blood pressure surge and Coronary Microvascular Dysfunction.Methods 58 cases of patients with hypertension in our hospital were given 24 h ambu-latory blood pressure monitoring(ambulatory blood pressure monitoring,ABPM).The coronary microvascular dys-function was estimated by the index of microcirculatory resistance(IMR). All cases were given biochemical test-ing,included TCH,TG,HDL-c,LDL-c and SUA.Results According to whether ABMP was arise,the patient were divided into MBPS group(n=21)and the Non-MBPS group(n=37).24 h,day,night and morning peak of systolic blood pressure were significantly higher in the morning peak group than in the average morning peak group. Multiple linear regression analysis showed that,MBPS,24 h average systolic blood pressure,day average systolic blood pressure,night average systolic blood pressure,and age were independent risk factors for coronary artery disease.Conclusion Morning blood pressure surge is closely related to severity of coronary microcirculation dysfunction. It is an independent risk factor for coronary microcirculation dysfunction. To control the blood pres-sure in patients with hypertension effectively can reduce morning peak target organ damage.
