Clinical Evaluation of High-Sensitive Troponin T in Acute Myocardial Infarction
10.3969/j.issn.1006-5725.2017.24.035
- VernacularTitle:超敏肌钙蛋白T在急性心肌梗死中的临床诊断价值
- Author:
Shuyuan WANG
1
,
2
;
510240 广州市海珠区妇幼保健院检验科
;
Ruifang CHEN
;
Jinde LIANG
;
Xuelian FAN
;
Lirong OU
;
Shaoxin YUAN
;
Peifeng KE
Author Information
1. 510120 广州市,广东省中医院检验科
2. 510240 广州市海珠区妇幼保健院检验科
- Keywords:
high-Sensitive Troponin T(hs-TnT);
acute myocardial infarction(AMI);
coronary angi-ography
- From:
The Journal of Practical Medicine
2017;33(24):4160-4164
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the diagnostic value of High-Sensitive Troponin T(hs-TnT)in acute myocardial infarction(AMI). Methods One hundred and sixty nine patients with serum hs-TnT concentration≥0.014 μg/L in early hospitalization were enrolled in this study.The ROC curve was used to compare the concentra-tion of hs-TnT with four heart enzyme(CK,CK-MB,LDH,AST)on the diagnostic efficacy to AMI. The differ-ence of hs-TnT in different clinical data groups were investigated using Mann-Whitney U rank test.Then the correla-tion between hs-TnT and Gensini score of Coronary angiography was investigated using the Spearman rank correla-tion test.Results The concentration of hs-TnT in patients with chest pain was significantly higher than that in non-AMI group(P<0.05).The AUC of each ROC curve was hs-TnT(0.806)>CK-MB(0.792)>CK(0.780)>AST (0.704)> LDH(0.684). The optimal diagnostic point of hs-TnT was 0.152 ug/L(sensitivity 0.659,specificity 0.894,Yuden index 0.553).There was a positive correlation between hs-TnT and Gensini scores in men,age>65 years old and the chest tightness group(P < 0.05). Conclusion The hs-TnT is better than four heart enzyme in early diagnosis of AMI and benefit early treatment of AMI.
