Correlation of etomidate and bispectral index in anesthesia induction of children with congenital heart disease shunting from left to right
10.3969/j.issn.1674-8115.2017.12.012
- VernacularTitle:依托咪酯用量对左向右分流先天性心脏病患儿血流动力学及脑电双频指数的影响
- Author:
Chun WANG
1
;
e Chang ZHU
;
ji Sai ZHANG
;
dong Wen HAN
;
Rong WEI
Author Information
1. 上海市儿童医院 上海交通大学附属儿童医院麻醉科
- Keywords:
etomidate;
bispectral index;
congenital heart disease;
children
- From:
Journal of Shanghai Jiaotong University(Medical Science)
2017;37(12):1650-1652
- CountryChina
- Language:Chinese
-
Abstract:
Objective·To explore the correlation of etomidate dose and bispectral index (BIS) in children with congenital heart disease shunting from left to right during anesthesia induction. Methods·After general anesthesia induction to 24 children with congenital heart disease shunting from left to right, sevoflurane inhaling was stopped in order to make the BIS value gradually return to 80. Intravenous injection of etomidate was sustained by 0.3 mg/(kg·min) until the BIS value reached 40. The heart rate (HR), arterial blood pressure (ABP) and central venous pressure (CVP) of the patients were recorded when BIS value was 80, 70, 60, 50,and 40, respectively.The correlation of etomidate dose and BIS value in the children during anesthesia induction was analyzed. Results·There were no significant hemodynamic changes when the BIS value were from 80 to 40. The amount of etomidate was highly negatively correlated with the BIS value (r=-0.769, P<0.01), the average dose of etomidate in children under 2 years of age was significantly higher than that in children over 2 years old (P=0.034). Conclusion·The etomidate dose is highly negatively correlated with the BIS value. Etomidate has less influence on hemodynamic parameters of children with congenital heart disease shunting from left to right. The BIS value may have relationship with patients'age.
