Ganglioneuroma Associated with Von Recklinghausen Neurofibromatosis.
- Author:
Won Chae LEE
1
;
Byung Min OH
;
Yun Hwan JANG
;
Seok Jong LEE
;
Sang Lip CHUNG
;
Soo Kyung LEE
;
Han Ik BAE
Author Information
1. Department of Dermatology, Kyungpook National University School of Medicine, Daegu, Korea. seokjong@knu.ac.kr
- Publication Type:Case Report
- Keywords:
Ganglioneuroma;
Skin;
von Recklinghausen neurofibromatosis
- MeSH:
Ganglion Cysts;
Ganglioneuroma*;
Mediastinum;
Neoplasm Metastasis;
Neuroblastoma;
Neurofibroma;
Neurofibromatoses*;
Schwann Cells;
Skin
- From:Korean Journal of Dermatology
2003;41(4):470-473
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Ganglioneuroma is the benign tumor exclusively composed of fully differentiated mature ganglion cell, Schwann cells and fibrous tissue. It develops most commonly in the posterior mediastinum and retroperitoneum but cutaneous involvement is exceedingly rare. Cutaneous tumor showing ganglion cells includes the following three entities: 1) primary ganglioneuroma, 2) well differentiated cutaneous metastasis from neuroblastoma, and 3) ganglioneuroma associated with von Recklinghausen's neurofibromatosis. Among them, the third has been considered as a neurofibroma with entrapment of ganglion cell. We described 2 cases of ganglioneuroma associated with von Recklinghausen neurofibromatosis and reviewed the histopathological and immunohistochemical findings.
