Application of Real World Fufang Kushen Injection in Treatment of Ovarian Malignant Tumor Based on Electronic Medical Data of Hospital Information System
10.3969/j.issn.1005-5304.2018.01.019
- VernacularTitle:基于医院信息系统电子医疗数据的复方苦参注射液治疗卵巢恶性肿瘤真实世界应用特征研究
- Author:
Cheng LI
1
;
ming Yan XIE
;
Yin ZHANG
;
Cen CHEN
;
Yan ZHUANG
Author Information
1. 中国中医科学院中医临床基础医学研究所
- Keywords:
Fufang Kushen Injection;
ovarian malignant tumor;
realworld;
hospital information system;
electric medical records
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2018;25(1):89-93
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the population characteristics, diagnostic characteristics and drug characteristics of patients with ovarian malignant tumor in the real world; To provide references for the clinical rational use of Fufang Kushen Injection.Methods Based on the electronic medical data warehouse of hospital information system of 39 hospitals from nationwide,the use of Fufang Kushen Injection in the treatment and diagnosis of electronic health data in patients with ovarian malignant tumor from August 2003 to December 2014 were extracted. Analysis of frequency and rate were based on the description of the demographic information, diagnosis information, records information such as the characteristics of prescription drugs. Result Data of 22 hospitals, including 1510 cases of patients with ovarian malignant tumor. The average age of patients was (54.93±12.75) years old, and obstetrics and gynecology department and oncology department had the most hospitalized patients, and outpatient admission is the most common hospitalized way. The single dose was (14.53±4.24)mL, and the course of treatment was (6.62±5.49)d.In the treatment of ovarian malignant tumors, combined western medicines were mainly anti-tumor chemotherapy drugs, immunomodulators, hepatoprotective agents, H1 receptor antagonists and electrolyte balance regulator, while combined TCM were clearing heat and antidote medicine, tonifying yang qi medicine, tonifying qi medicine, regulating qi medicine, and hemostatic medicine. The total effective rate was 47.85%. Conclusion Population characteristics of Fufang Kushen Injection in the treatment of ovarian malignant tumors are clear;and the real world clinical dosage, course of treatment with instructions related to define the scope of the basic varieties. Clinical combination has a wide range of drugs.
