Analysis on influence of transsphenoidal approach pituitary adenoma resection in patients with complicating cardiomyopathy on serum growth hormone level and cardiac structural function
10.3969/j.issn.1671-8348.2017.36.009
- VernacularTitle:经鼻蝶窦垂体瘤切除术对合并心肌病患者血清生长激素水平及心脏结构功能的影响分析
- Author:
Junyi GU
1
;
Xiangdong LI
;
Zhong WANG
;
Zhengquan YU
;
Youxin ZHOU
;
Gang CHEN
;
Yuchao CHEN
;
Yuzhao LIU
Author Information
1. 苏州大学附属第一医院神经外科
- Keywords:
pituitary neoplasms;
myocardial thickening;
growth hormone;
pituitary tumur resection
- From:
Chongqing Medicine
2017;46(36):5065-5067
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the surgical treatment and clinical effect of growth hormone type pituitary tumor complica-ting cardiomyopathy .Methods Sixty-five cases of growth hormone type pituitary adenoma complicating cardiomyopathy in the hos-pital from June 2012 to June 2016 were selected and performed transsphenoidal approach pituitary adenoma resection .Then serum growth hormone level ,ECG results ,ultrasound cardiogram results and clinical symptoms were observed at 2 weeks after operation . Results The signs were significantly improved after surgery ,acromegaly and nasolabial hypertrophy were significantly improved , dizziness ,fatigue ,hypertension and hyperglycemia were significantly improved ;the average postoperative growth hormone level was (4 .37 ± 2 .03)μg/L ,which was significantly lower than (40 .27 ± 4 .18)μg/L before operation ,and the difference was statistically significant (P< 0 .01 );postoperative IVST ,LVIDd and LVPWT were significantly lower than those before operation ,and the difference was statistically significant (P<0 .01);postoperative average E/A and LVEF were significantly lower than those before operation ,and the difference was statistically significant (P<0 .01) .Conclusion Transsphenoidal pituitary tumor resection can re-duce the level of grow th hormone and improves the cardiac function .
