Progress of galectin-3 and atrial fibrillation
10.11958/20170636
- VernacularTitle:半乳糖凝集素-3与心房颤动的研究进展
- Author:
meng Rui LIU
1
;
le Chang LIU
Author Information
1. 天津市心血管病离子与分子机能重点实验室
- Keywords:
atrial fibrillation;
galectin-3;
atrial remodeling;
inhibitor;
review
- From:
Tianjin Medical Journal
2017;45(12):1330-1333
- CountryChina
- Language:Chinese
-
Abstract:
Atrial fibrillation (AF) is the most common tachyarrhythmia in clinical practice. Owing to its high morbidity and mortality, early diagnosis of AF plays an important clinical significance in treatment and prognosis. Galectin-3 (Gal-3), as a sensitive marker of inflammatory and oxidative stress found in recent years, is involved in the occurrence and development of myocardial inflammation and fibrosis, which is closely related to atrial remodeling. Gal-3 inhibitor may decrease the risk of AF by reversing myocardial remodeling, which may provide a new theoretical basis and research direction for the upstream treatment of AF.
