Comparative Study on Ultra-early and Early Enteral Nutrition Support in Elderly Obese Patients With Severe Acute Pancreatitis
10.3969/j.issn.1008-7125.2017.12.008
- VernacularTitle:超早期和早期肠内营养对老年肥胖重度急性胰腺炎疗效的对比研究
- Author:
Yueji NING
1
;
Qi PAN
;
Boneng MAO
;
Guochang CHEN
;
Qian LIU
;
Xinfang XU
Author Information
1. 江苏省宜兴市人民医院消化内科 214200
- Keywords:
Severe Acute Pancreatitis;
Aged;
Obesity;
Ultra-Early Enteral Nutrition;
Therapy
- From:Chinese Journal of Gastroenterology
2017;22(12):744-747
- CountryChina
- Language:Chinese
-
Abstract:
Background:Early administration of enteral nutrition can improve intestinal mucosal barrier in patients with severe acute pancreatitis (SAP),reduce infection and complications;but when should the enteral nutrition be started is still controversial. Aims:To study the effect of different initiation time of enteral nutrition on elderly obese patients with SAP. Methods:The clinical efficacy,hospitalization time,hospitalization cost and the risk of complication were analyzed retrospectively in the two groups of patients with either ultra-early enteral nutrition (group A)or early enteral nutrition (group B),as well as the serum levels of inflammatory cytokines before and after treatment. Results:No significant difference in total effective rate was found between group A and group B (90. 9% vs. 79. 2%,χ2 = 1. 227,P > 0. 05). Compared with group B,the recovery time of blood and urine amylase,and hospitalization time in group A were significantly shortened and the cost of hospitalization was significantly decreased (P < 0. 05). The time of abdominal pain, bloating,vomiting and fever in group A was significantly shorter than that in group B (P < 0. 05). After 14 days of treatment,levels of IL-6,TNF-α and CRP in group A were significantly lower than those in group B (P < 0. 05). The incidence of infection was significantly lower in group A than in group B (P < 0. 05). Conclusions:Compared with early enteral nutrition group,ultra-early enteral nutrition for elderly obese patients with SAP has better efficacy,and has a shorter hospital stay and lower hospitalization cost.
