Progress on clinical application of RGD tripeptide
- VernacularTitle:RGD三肽的临床应用进展
- Author:
li Shu NIU
1
;
Xiao PANG
;
Li ZHOU
;
ping Su LI
Author Information
1. 川北医学院附属医院核医学科
- Keywords:
Arg-Gly-Asp( RGD);
integrin;
molecular image;
anti-tumor;
anti-inflammatory
- From:
Basic & Clinical Medicine
2018;38(1):107-111
- CountryChina
- Language:Chinese
-
Abstract:
The integrin is a family of membrane receptor proteins composed of heterologous dimer , it can identify the sequence RGD .Integrin excessive expressed in tumor cells and angiogenesis .Using their special relationship a-mong them, the RGD as the carrier, combined with the radioactive tracer , antineoplastic drugs and other substances,which has tumoraffin imaging ,targeted anticancer therapy ,anti-inflammatory,anti depression effect and bone and nerve repair , and so on .
