Application of blood purification in renal impairment of multiple myeloma
- VernacularTitle:血液净化治疗多发性骨髓瘤肾脏损害
- Author:
Lei ZHANG
1
;
meng Li CHEN
Author Information
1. 中国医学科学院北京协和医学院北京协和医院肾内科
- Keywords:
plasmapheresis;
high cut-off hemodialysis;
renal impairment of multiple myeloma;
cast nephropathy;
serum free light chain
- From:
Basic & Clinical Medicine
2018;38(1):112-117
- CountryChina
- Language:Chinese
-
Abstract:
Renal impairment is common in multiple myeloma .Besides effective chemotherapy , direct removal of se-rum free light chain by plasmapheresis or high cut-off hemodialysis is also important in the treatment of renal im-pairment in multiple myeloma .Based on results of the randomized controlled trials , the role of plasmapheresis in treating renal disease of multiple myeloma is debated .On the other side , high cut-off hemodialysis is novel and re-cently developed .Many studies have shown its potential function to further increase renal response rate when com -bined with chemotherapy .
