Progress of Visual Biosensor Based on Gold Nanoparticles
10.11895/j.issn.0253-3820.171054
- VernacularTitle:基于金纳米材料的可视化生物传感器的研究进展
- Author:
Ming Xiao MA
1
;
Mi SUN
;
Yue LIN
;
Jin Yin LIU
;
Fang LUO
;
Hua Long GUO
;
Bin QIU
;
Yu Zhen LIN
;
Nan Guo CHEN
Author Information
1. 食品安全与生物分析教育部重点实验室
- Keywords:
Gold nanoparticles;
VisualiZation biosensor;
Review
- From:
Chinese Journal of Analytical Chemistry
2018;46(1):1-10
- CountryChina
- Language:Chinese
-
Abstract:
VisualiZation detection methods are used for determination of the concentration of unknown target by comparing the color change in the intensity or type of reaction solution by naked eye.VisualiZation detection method has some advantages such as simple and rapid operation, low detection cost, fast reaction speed, and detecting target concentration by means of naked eye.Gold nanomaterials are widely used in the construction of visual biosensors due to its unique optical properties.For example, when changing the distance or morphology of the particles, the plasmon resonance absorption peak of local surface will change accordingly.Herein, we reviewed the application of gold nanomaterials in visualiZation biosensors for the detection of target molecules, summed up the main problems of AuNP colormertic methods in the determination of actual samples, and provided an outlook of the future of gold nanoparticles-based biosensor in application development.
