MR texture analysis in differential diagnosis of glioblastoma and solitary metastatic brain tumor

VernacularTitle:MR纹理分析鉴别诊断脑胶质母细胞瘤和单发转移瘤的价值
Author: Minhong WANG ¹ ; Zhan FENG
Author Information

1. 皖南医学院第一附属医院医学影像中心
Keywords: Glioblastoma; Neoplasm metastasis; Magnetic resonance imaging; Texture analysis
From: Chinese Journal of Medical Imaging Technology 2017;33(12):1784-1787
CountryChina
Language:Chinese
Abstract: Objective To explore the value of MR texture analysis in differential diagnosis of glioblastoma and solitary metastasis.Methods Thirty-five patients with brain glioblastomas and forty patients with brain metastases confirmed by pathology or clinic were enrolled.All patients underwent conventional MR scan and enhanced examination,including T1 FLAIR,T2WI,T2 FLAIR,DWI,and enhanced T1WI.Texture features of the lesions were extracted with MaZda software by manually drawing ROI on the maximum level of tumor delineation in DWI and enhanced T1WI.Results There were statistical differences between glioblastoma and solitary metastasis of enhanced T1WI skewness in the histogram class texture parameters,gray co-occurrence matrix parameters including enhanced T1WI image correlation,mean and DWI correlation.Logistic regression analysis showed the area under ROC curve of the model was 0.834.Conclusion Texture analysis can provide reliable and quantified objective basis for differential diagnosis of glioblastoma and solitary metastatic brain tumor.