Clinical effect of iliac artery interventional chemotherapy combination with bladder perfusion for high level of bladder urothelial carcinoma
10.3760/cma.j.issn.1673-4203.2017.09.003
- VernacularTitle:髂内动脉灌注联合膀胱灌注用于高级别膀胱癌的临床研究
- Author:
Jiansen CHEN
1
;
Ming LI
;
Yueqing WU
;
Mao TANG
;
Zetian TANG
;
Xinwu GUO
;
Jinqian LI
;
Kesong QIN
Author Information
1. 南阳市第二人民医院泌尿外科
- Keywords:
Urinary bladder neoplasms;
Chemotherapy,cancer,regional perfusion;
Case-control studies;
Internal iliac artery chemotherapy;
High level
- From:
International Journal of Surgery
2017;44(9):583-586,后插1
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the clinical effect of iliac artery interventional chemotherapy combination with bladder perfusion for high level of bladder urothelial carcinoma after transurethral bladder tumor electricity cut operation for those who intend to retain the bladder.Methods From February 2010 to December 2016,a total of 74 cases high-grade urothelial carcinoma of the bladder,giving chemotherapy and suitted support were retrospectively analyzed.The patients were divided into two groups according to different chemotherapy methods.Artery perfusion chemotherapy group:43 cases treated by transurethral bladder tumor cutting + bilateral iliac artery interventional perfusion chemotherapy + bladder perfusion in combination therapy;Intravenous chemotherapy group:31 cases underwent transurethral bladder tumor cut method + cisplatin,vein gemcitabine + bladder perfusion chemotherapy combined therapy.According to the ((x) ± s) between the groups.The method of count data is represented by chi-square test.Kaplan-meier method was used to describe the survival time of two groups of patients after operation.Results Two groups of patients with postoperative there was no statistically significant difference in disease-free survival time.In the bone marrow suppression (x2 =4.956,P =0.029);gastrointestinal tract reaction (x2 =5.912,P =0.012);dermatitis,mucositis (x2 =4.276,P =0.013),etc.,has the advantages in the iliac artery interventional perfusion chemotherapy (P ＜ 0.05).Conclusion Via efficient iliac arterial infusion chemotherapy in patients with venous chemotherapy patients,to the retention of the bladder has a certain value,and the incidence of adverse reactions after surgery is low,have certain advantages.
