Solitary fibrous tumor of the pelvis: report of 5 cases and review of literatures
10.3760/cma.j.issn.1673-4203.2017.09.006
- VernacularTitle:盆腔孤立性纤维性肿瘤五例分析并文献复习
- Author:
Tong ZHANG
1
;
Lei LIANG
;
Erwei GUO
Author Information
1. 北京市普仁医院泌尿外科
- Keywords:
Pelvic neoplasms;
Pathology,clinical;
Surgical procedures,operative;
Solitary fibrous tumor
- From:
International Journal of Surgery
2017;44(9):595-598,后插1
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinic pathologic characteristics,pathologic diagnosis,differential diagnosis management of solitary fibrous tumor and improve the level of its diagnosis and treatment.Methods This was a retrospective analysis of clinical data and pathological features in 5 cases of solitary fibrous tumor of pelvis from March 2002 to December 2016,and the related literatures were also reviewed.Solitary fibrous tumor was male predominance(4 males;1 females)and the age ranged from 32 to 62 years with an average of 52 years.Four patients presented with a mass in pelvis which was found incidentally in a comprehensive medical examination.One patient was afflicted flank pain.CT imagine examinations showed that most of the solitary fibrous tumor were well-defined soft tissue masses with intense enhancement.1 case exhibited myxomatoid changes.Only 1 case showed typical manifestations of fibrous tissue on MRI scan.All of these patients were successfully treated with open surgical resection of tumor.Results The operation was successful in the 5 cases.The average operation time was 260 min.The average blood loss was 1 200 ml.Pathologic examination revealed solitary fibrous tumor.Histologically,the neophlasm were composed of round and oval cells.The most essential characteristic was monatypical spindle-shaped tumor cells on a collagenous background.Keloid-type collagen,hypocellular and hypercellular areas could be observed in all the cases,and mitoses was rare.Immunohisto-chemically,the tumor cells were positive for vimentin,CD99,Bcl-2 in five cases,but negative for CK,SMA in all cases.There was recurrence in one patient with a median follow-up of 9 (2-26) months,and no metastasis in 4 patients.Conclusions Solitary fibrous tumor of the pelvis is a rare tumor which has no special characteristics in clinical and iconography,and its diagnosis mainly depend on the histopathologic features and immunohistochemistry.Completely resection of tumor could usually cure the disease,while careful follow-up is still necessary.
