Advances in Study on Novel Biological Agents in Treatment of Inflammatory Bowel Disease
10.3969/j.issn.1008-7125.2017.11.009
- VernacularTitle:新型生物制剂治疗炎症性肠病的研究进展
- Author:
Jiayan MAO
1
;
Ling LI
;
Zhi PANG
Author Information
1. 苏州大学附属第一医院消化科 215006
- Keywords:
Inflammatory Bowel Disease;
Crohn Disease;
Colitis,Ulcerative;
Therapy;
Biological Agents
- From:
Chinese Journal of Gastroenterology
2017;22(11):692-695
- CountryChina
- Language:Chinese
-
Abstract:
Inflammatory bowel disease (IBD) is a chronic,non-specific intestinal inflammatory disease.Traditional drug therapy includes aminosalicylates,glucocorticoids and immunosuppressive agents,and their long-term use will induce multiple side effects,and having high recurrence rate and poor efficacy in critically ill patients.Studies have shown that biological agents are effective in inducing and maintaining remission in patients with IBD,promoting mucosal healing,and improving the quality of life.With the in-depth study of pathogenesis of IBD,researches on the development of novel biological agents have been performed widespreadly.This article reviewed the advances in study on novel biological agents in treatment of IBD.
