Quantitative analysis on content of different components in Curcumae Aromaticae Radix by QAMS

VernacularTitle:一测多评法测定毛郁金中5种成分
Author: ling Qing GUO ¹ ; jun Fu ZHOU ; Qi SHAN ; hua Jing HUANG ; zhu Xi WANG ; Jie HUA ; Miao WANG ; bin Wen HOU
Author Information

1. 天津中医药大学
Keywords: quantitative analysis of multi-component with a single-marker (QAMS); Curcumae Aromaticae Radix; curdione; curcuma diol; ocathydro-1,4-dihydroxy-1,4-dimethyl-7-(propan-2-ylidene)azulen-5(1H)-one; original curcumol; curcumin
From: Drug Evaluation Research 2017;40(9):1274-1278
CountryChina
Language:Chinese
Abstract: Objective To develop a method of quantitative analysis of multi-components by single marker (QAMS) for simultaneously determining five compounds in Curcumae Aromaticae Radix.Methods An HPLC method was developed as QAMS to determine curcuma diol,ocathydro-1,4-dihydroxy-1,4-dimethyl-7-(propan-2-ylidene)azulen-5(1H)-one,original curcumol and curcumin in Curcumae Aromaticae Radix,using curdione as intermal reference substance,and the relative correction factor (RCF) of the four components was determined by HPLC with good reproducibility.Their contents in 10 batches of samples,collected from different areas,were determined by both external standard method and QAMS.Result No significant differences were found in the quantitative results of four compounds in 10 batches of Curcumae Aromaticae Radix determined by external standard method and QAMS.Conclusion It is feasible and suitable to evaluate the quality of Curcumae Aromaticae Radix by QAMS.