Clinical observation on Danshen Chuangxiongqin Injection in treatment of posterior circulation ischemia vertigo
10.7501/j.issn.1674-6376.2017.09.029
- VernacularTitle:丹参川芎嗪注射液治疗后循环缺血性眩晕的临床评价
- Author:
jing Zhen XU
1
Author Information
1. 安徽省中医院,安徽合肥230031
- Keywords:
Danshen Chuangxiongqin Injection;
posterior circulation ischemia vertigo;
blood viscosity;
fibrinogen
- From:
Drug Evaluation Research
2017;40(9):1334-1337
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the clinical effect of Danshen Chuangxiongqin Injection in treatment of posterior circulation ischemia vertigo.Methods Patients (80 cases) with posterior circulation ischemia vertigo attack in Anhui Hospital of Traditional Chinese from March 2015 to March 2017 were randomly divided into control and treatment groups,and each group had 40 cases.Patients in control group were treated by Betahistine mesylate,6 mg/time (3 times/d) for 2 weeks.Patients in treatment group were iv administered with Danshen Chuangxiongqin Injection (10 mL/d) added into normal saline 250 mL,once daily for 2 weeks.After treatment,the efficacy was evaluated,and the levels of blood viscosity index,fibrinogen in two groups before and after treatment were compared.Results Total effective rate of observation group was 92.5％ which was higher than the control group's 72.5％ with significant difference (P ＜ 0.05).After treatment,the laboratory indexes (levels of blood viscosity,fibrinogen,and so on) were decreased,the improvement degree of these indexes in treatment group were significantly better than those in control group,with significant difference between two groups (P ＜ 0.05).Conclusion Danshen Chuangxiongqin Injection has significant effect in treating posterior circulation ischemia vertigo and it is worthy of clinical application and promotion.
