NF-κB and the onset and progression of hepatocellular carcinoma
10.3760/cma.j.issn.1008-1372.2017.11.048
- VernacularTitle:NF-κB与肝癌发生发展
- Author:
Shuhan XIONG
1
;
Ruitong GAO
;
Fanzhu MENG
;
Jinghui YANG
Author Information
1. 吉林大学公共卫生学院劳动卫生与环境卫生教研室
- Keywords:
NF-kappa B;
Liver neoplasms;
Review
- From:
Journal of Chinese Physician
2017;19(11):1758-1760,封3
- CountryChina
- Language:Chinese
-
Abstract:
Hepatocellular carcinoma is one of the malignant tumors with highest mortality.Nuclear factor κB (NF-κB) as the mediator of many pathways,such as metabolic pathway,angiogenesis and adherence factor,is implicated in the onset and progression of hepatocellular carcinoma.Through the literature retrieval,the activity of NF-κB and its implication in the onset,progression,invasion and metastasis have been reviewed in the article.