Research progress of the relationship between 14-3-3ζ and malignant tumor
10.11904/j.issn.1002-3070.2017.06.012
- VernacularTitle:14-3-3ζ与恶性肿瘤关系的研究进展
- Author:
Xuejiao HAN
1
;
Yanchun LI
;
lichun SUN
Author Information
1. 哈尔滨医科大学附属肿瘤医院内四科 哈尔滨 150081
- Keywords:
14-3-3ζ;
Malignant tumors;
Treatment
- From:
Practical Oncology Journal
2017;31(6):543-547
- CountryChina
- Language:Chinese
-
Abstract:
The 14-3-3 protein is a highly conserved acidic polypeptide family involved in intracellular signaling,protein transportation, cell proliferation, invasion, migration, and apoptosis. Many studies have shown that 14-3-3ζhas a high expression level in many malignant tumors. This paper introduces the structure of 14-3-3ζ,the biological function,and the development of the malignant tumor ( breast cancer,lung cancer,hepatocel-lular carcinoma,glioma,head and neck neoplasms) related to the development of 14-3-3ζand treatment of ma-lignant tumor in order to provide valuable information and ideas.
