Study of therapeutic effects of Alprostadil Injection and Composite Salvia Injection on diabetic foot
10.7501/j.issn.1674-6376.2017.11.023
- VernacularTitle:前列地尔注射液联合复方丹参注射液治疗糖尿病足的疗效研究
- Author:
Bing JIN
1
;
lin Yong CAI
;
peng Jun WANG
Author Information
1. 北京市昌平区中西医结合医院创伤骨科
- Keywords:
Alprostadil Injection;
Composite Salvia Injection;
Diabetic foot
- From:
Drug Evaluation Research
2017;40(11):1638-1641
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the therapeutic effects of Alprostadil Injection and Composite Salvia Injection on diabetic foot.Methods Selected 210 cases of patients with diabetic foot who were treated in our hospital from January 2012 to December 2016,divided into three groups randomly.The group A was treated with Alprostadil Injection,group B was treated with Composite Salvia Injection,the group C was treated with Alprostadil Injection and Composite Salvia Injection.The clinical therapeutic effects of the three groups were compared,and the levels of blood lipid,urea nitrogen,creatinine,beta-globulin and urinary microalbumin before and after treatment were compared.Results After treatment,the effective rate of the group C was 92.86％ (65/70),significantly higher than that of the group A and B (P ＜ 0.05).After treatment,the levels of TG,TC and LDL-C in the three groups were significantly lower than before treatment (P ＜ 0.05),HDL-C levels were significantly higher than before treatment (P ＜ 0.05),and the group C was more significant (P ＜ 0.05).After treatment,the levels of urea nitrogen,creatinine,beta 2 and urinary microalbumin were significantly decreased in the three groups than before (P ＜ 0.05),and the group C was more significant (P ＜ 0.05).Conclusion The effect of Alprostadil Injection and Composite Salvia Injection on diabetic foot is better,which is safe and effective.
