Research progress on polysaccharide of Chinese materia medica against gastrointestinal tumors in vitro experiments
10.7501/j.issn.1674-6376.2017.11.027
- VernacularTitle:中药多糖体外抗胃肠肿瘤作用的研究进展
- Author:
wei Feng XU
1
;
yan Jing MENG
Author Information
1. 天津中医药大学,天津300193
- Keywords:
polysaccharide of Chinese materia medica;
natural compound;
anti-tumor;
gastric tumor cells line;
intestinal tumor cell line
- From:
Drug Evaluation Research
2017;40(11):1659-1663
- CountryChina
- Language:Chinese
-
Abstract:
Tumor is a seriously disease that endanger human health.Gastrointestinal cancer is one of the most prevalent types of digestive system cancers among the Chinese population.While radiotherapy and chemotherapy kill cancer cells,their toxicity to normal cells cannot be ignored.Hence,polysaccharides from Chinese materia medica (CMM) have been the focus of anti-tumor research,as they can improve functions of the immune system and do not harm to normal cells.In this review,we have analyzed the recent advances in the study of the effects of polysaccharides from CMM on human gastric cancer cell lines (MGC-803 and SGC-7901) and intestinal tumor cell lines (LoVo,HCT-116,and HT-29) in vitro.The purpose of this study is to provide a material basis for clinical research of polysaccharides from CMM.