Advances in gene expression profiling of metastases from unidentified primary tumor
10.11904/j.issn.1002-3070.2017.06.014
- VernacularTitle:原发灶不明转移癌基因表达谱分析技术进展
- Author:
Qian HAN
1
;
Lianjun LIN
Author Information
1. 北京大学第一医院老年科 北京 100034
- Keywords:
Cancer of unknown primary sites( CUP);
Gene expression profiling( GEP);
Progress in di-agnosis
- From:
Practical Oncology Journal
2017;31(6):554-558
- CountryChina
- Language:Chinese
-
Abstract:
Primary lesions unknown metastatic cancer ( CUP) is a class of histopathologically confirmed metastases. However,a variety of clinical diagnosis and treatment can not clear the primary tumor. The identifica-tion of tumor primary site is the first step in the diagnosis of CUP. The histopathology,immunohistochemistry and PET /CT are commonly used clinical diagnosis and treatment. Gene expression profiling technique is a new meth-od for the diagnosis of primary tumor in recent years. It has high diagnostic accuracy,sensitivity and specificity, and is expected to achieve individual treatment of patients with CUP.
