Preoperative planning of laparoscopic ultrasound-guided I125 implantation in treatment of pancreatic cancer based on CT images
10.13929/j.1672-8475.201708018
- VernacularTitle:基于CT图像的腹腔镜超声引导I125粒子植入治疗胰腺癌术前规划
- Author:
Fang LIU
1
;
Zhiyong YANG
;
Daguang ZHANG
;
Shan JIANG
Author Information
1. 天津大学机械工程学院图像导航放射治疗系统实验室
- Keywords:
Radiotherapy;
Iodine isotopes;
Pancreatic neoplasms;
Ultrasonography;
Laparoscopy
- From:
Chinese Journal of Interventional Imaging and Therapy
2017;14(12):763-767
- CountryChina
- Language:Chinese
-
Abstract:
Objective To propose a novel preoperative planning method for laparoscopic ultrasound-guided implantation of I125 seeds in treating pancreatic cancer based on CT images,and to evaluate the feasibility of this treatment.Methods CT images of a pancreatic cancer patient were transmitted into the treatment planning system (TPS) developed by our laboratory,to obtain three-dimensional representations of the tumor and surrounding organs.All the positions of puncture were selected with the aid of virtual template,then possible needle paths and the number of necessary I125 seeds were planned,and the radiation dose was evaluated.Results A total of 21 needle paths with 45 seeds implantation into the tumor were planned.In the preoperative planning,the dosage parameters D90 and V100 of the tumor were 12 481 cGy and 92.83％,which was relatively eligible for the clinic requirement,whereas of suurounding non-tumor pancreatic tissue was 0 and 0.40％,respecyively.Conclusion Laparoscopic ultrasound-guided implantation of I125 seeds can be considered as a useful method for treating pancreatic cancer with accurate implantation of 125I seeds and satisfying effect of local control for the tumor in theory.
