Research advances in picornavirus 2C gene and its encoding protein
10.3969/j.issn.1002-2694.2017.11.014
- VernacularTitle:小RNA病毒2C基因及其编码蛋白的研究进展
- Author:
si Xiao TANG
1
;
chun An CHENG
;
shu Ming WANG
Author Information
1. 四川农业大学动物医学院禽病防治研究中心
- Keywords:
picornavirus;
2C gene;
encoding protein
- From:
Chinese Journal of Zoonoses
2017;33(11):1024-1028
- CountryChina
- Language:Chinese
-
Abstract:
Picornaviridae 2C gene is relatively conservative,whose encoded protein is a non-structural protein.The 2C protein is in an earlier detection and only can be detected during virus replicatin.The 2C protein has multiple fuctions:the role of AAA+ helicase activity,invasion cells by autophagy pathway,abduction cells on inflammation and apoptosis;the interaction with other proteins such as 2B and 3C that might be induced by 2C protein,which can participate in the pathogenic process in a way.Above all,we mainly outline the reseach advances on Picornaviridae 2C gene and its encoded protein,in order to provide some superficial reference for its further study.
