Therapeutic effect of focused ultrasound on rabbit ear acnevv
10.3969/j.issn.1671-8348.2017.34.003
- VernacularTitle:聚焦超声对兔耳痤疮的治疗效果研究
- Author:
Xiaoyong DONG
1
;
zhangyou GUO
;
Qingyi LI
;
Yunchang LIU
;
Yu TIAN
;
Fangying ZHONG
;
Jianzhong ZOU
Author Information
1. 重庆医科大学生物医学工程学院/省部共建国家重点实验室培育基地-重庆市超声医学工程重点实验室/重庆市生物医学工程学重点实验室/重庆市微无创医学协同创新中心 400016
- Keywords:
focused ultrasound;
rabbit ear acne;
effectiveness
- From:
Chongqing Medicine
2017;46(34):4763-4765,4770
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the feasibility and effectiveness of focused ultrasound on the acne of rabbit ear.Methods Eighteen male rabbits were randomly divided into blank control group,model control group and ultrasound irradiation group.Acne rabbit ear model was established by Kligman's method in model control group and ultrasound irradiation group.Then,continuous ultrasonic irradiation was given in ultrasound irradiation group.Pathological changes were observed at the time of before and after ultrasound irradiation and 14 days after ultrasound irradiation.Results After modeling,hair follicle expansion,hyperkeratosis,acupoint hypertrophy were observed in blank control group.Compared with blank control group,the thickness of horn layer,the sebaceous gland diameter and other index in model controlgroup were statistically significant (P＜0.01);After irradiation,there were hyperemia and edema in epidermis,angiotelectasis and inflammatory infiltrating,but coagulative necrosis in slice was not observed,14 days later,hair follicle mild expansion,mild keratosis,spiny thinning were observed in ultrasound irradiation group,when compared with model control group,the thickness of horn layer,sebaceous gland diameter and other index were decreased in ultrasound irradiation group,and the differences were statistically significant(P＜0.01).Conclusion The ultrasonic focusing treatment on rabbit ear acne is feasible and effective.
