Clinical value of preoperative 18F-FDG PET-CT imaging in staging of colorectal cancer
10.3760/cma.j.issn.1006-9801.2017.12.004
- VernacularTitle:术前18F-FDG PET-CT显像对结直肠癌分期的临床价值
- Author:
Rongrong TIAN
1
;
Yunfeng BO
;
Yixun ZHANG
;
Hongxing JIN
;
Ming ZHAO
;
Hongyu ZHANG
Author Information
1. 山西省肿瘤医院PET-CT中心
- Keywords:
Colorectal neoplasms;
Neoplasm staging;
Positron-emission tomography;
Fluorodeoxyglucose F18
- From:
Cancer Research and Clinic
2017;29(12):809-814
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss the value of preoperative 18F-FDG PET-CT imaging in the staging of colorectal cancer. Methods Eighty-three patients with colorectal cancer were studied who underwent 18F-FDG PET-CT examinations without any previous treatment and subsequent operations within one week. The results of PET-CT and pathology were analyzed with chi-square test and Kappa consistency test. Results The diagnostic accuracy of primary colorectal lesions was 100 %, the average of maximum standardized uptake value(SUVmax) was 14.54±8.10(4.43-48.19). The diagnostic accuracy of local infiltration depth, lymph node metastasis, distant metastasis and TNM staging before operation were 73.49 %(61/83), 90.36 %(75/83), 97.59 % (81/83) and 85.54 % (71/83), respectively, and the Kappa values were 0.481, 0.797, 0.950, 0.788 (P <0.05).The diagnostic sensibility of staging with T1-2,T3and T4were 30.00 %(3/10),68.42 %(13/19) and 83.33 % (45/54), respectively, the diagnostic accuracy of staging with T1-2, T3and T4were 91.57 % (76/83), 74.70 % (62/83) and 80.72 % (67/83). Conclusion Preoperative 18F-FDG PET-CT imaging is an effective staging method for colorectal cancer, and has high accuracy in the detection of primary colorectal lesions, lymph node metastasis, distant metastasis and T4stage lesions, but it is difficult for diagnosing of the T1-2and T3lesions.
