Analysis of distribution of 15249 strains of nosocomial infection pathogens and drug resistance
10.3969/j.issn.1673-4130.2017.23.013
- VernacularTitle:15249株院内感染病原菌分布及耐药性分析
- Author:
Zhiyong LIU
1
;
Juan YUAN
;
Mei YANG
;
Hongying YUAN
;
Bo ZHANG
;
Junfu HUANG
;
Weiling FU
Author Information
1. 陆军军医大学第一附属医院检验科
- Keywords:
pathogen;
nosocomial infection;
drug susceptibility test;
drug resistance change;
multidrug resistant bacteria
- From:
International Journal of Laboratory Medicine
2017;38(23):3252-3256
- CountryChina
- Language:Chinese
-
Abstract:
Objective To monitor the distribution of pathogens and the drug resistance of inpatients in Southwest Hospital in ChongQing ,and to analyze the prevalence of pathogens in various departments .Methods A total of 15249 pathogens cultured from clinical specimens in our hospital in 2016 and the antimicrobial susceptibility testing results were retrospectively analyzed .The anti-microbial susceptibility testing was carried out by using the paper diffusion method (K-B) or the automated instrument method (MIC) .The data were analyzed by WHONET5 .5 software according to the standard of CLSI2017-M100 .Results Compared with 2015 ,a total of 15249 pathogenic microorganisms were isolated from the hospital in 2016 ,among which 9742 were Gram-negative bacteria ,down 11 .45% and 4188 were Gram-positive bacteria ,up 15 .34% and 1319 were fungi ,down 11 .48% .Top five depart-ments which collected most microbiological culture specimen were Burn ,Pediatric ,ICU ,Hepatobiliary surgery ,Neurosurgery .The main specimen type of culture was sputum ,accounting for 27 .28% ,followed by blood ,wound secretion ,urine ,abdominal fluid .The first five pathogens were Klebsiella pneumoniae ,Acinetobacter baumannii ,Escherichia coli ,Staphylococcus aureus ,Pseudomonas aeruginosa .Conclusion Gram-negative bacteria are mainly infected organisms in our hospital .However ,Gram-positive bacteria are also important pathogens .Antibiotics should be selected according to the results of antimicrobial susceptibility testing .The distribu-tion of pathogens and the changes of drug sensitivity should be emphasized ,which can provide an effective theoretical basis for treat-ment .
