Analysis of pathogens distribution and drug resistance of nosocomial infection in patients with end-stage diabetic nephropathy
10.3969/j.issn.1673-4130.2017.23.019
- VernacularTitle:终末期糖尿病肾病患者院内感染的病原菌分布及耐药性分析
- Author:
Xunhong LIANG
1
;
Jinsong WU
;
Jine CHEN
;
Wenqing LI
;
Weiyuan WU
;
Yuemei LU
Author Information
1. 深圳市人民医院检验科
- Keywords:
end-stage diabetic nephropathy;
nosocomial infection;
pathogen distribution;
drug resistance
- From:
International Journal of Laboratory Medicine
2017;38(23):3270-3273
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the pathogens distribution and drug resistance of nosocomial infection in patients with end-stage diabetic nephropathy .Methods 96 cases of end-stage diabetic nephropathy were randomly selected in our hospital .The speci-mens of urine ,blood and sputum were collected .The pathogens were identified by the drug susceptibility testing .Results The in-fection rate was 27 .08% .A total of 103 strains of pathogens were isolated ,including 15 strains of fungi ,42 strains of gram-negative bacteria and 46 strains of gram-positive bacteria .The drugs susceptibility rates of the fungi to flucytosine ,amphotericin B and flu-conazole were 100% ,and it also showed that the fungi had higher sensitivity to other common antibiotics ;the drug susceptibility rates of gram-positive bacteria to vancomycin and teicoplanin were 100% ,while its drug susceptibility ability to penicillin ,strepto-mycin and others were weak ;the drug susceptibility rates of gram-negative bacteria to piperacillin and imipenem were high ,while its drug susceptibility ability to aztreonam and cephalosporin were weak .Conclusion The low resistance in the patients with end-stage diabetic nephropathy the abuse of clinical antiseptic drugs lead to the dysbacteriosis ,resulting in a significant increase of the inci-dence of nosocomial infection ,so the analysis of pathogens distribution and drug resistance of nosocomial infection has clinical sig-nificance .
