Study on the diagnostic value of the ratio of ADA and CysC in the Pleural effusion and serum for Tuberculous pleural effusion
10.3969/j.issn.1673-4130.2017.23.021
- VernacularTitle:ADA、CysC在胸腔积液和血清中的比值对结核性胸腔积液的诊断价值研究
- Author:
Yingbin YE
1
;
Xiaoming YANG
;
Xiaofang WANG
;
Xiuxiang HUANG
;
Huifeng DONG
;
Jinyan LIU
;
Ping ZHANG
;
Xiao LI
;
Junyi WANG
Author Information
1. 河北省邯郸市传染病医院检验科
- Keywords:
cystatin C;
Adenosine Deaminase;
Tuberculous pleural effusion;
Receiver Operating Characleristic curve
- From:
International Journal of Laboratory Medicine
2017;38(23):3277-3279
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical value of the ratio of ADA and CysC in the Pleural effusion and serum for the di-agnosis of Tuberculous pleural effusion .Methods In the first half of 2014 ,50 cases from a random sample of patients with tubercu-lous pleurisy admitted in our hospital were chosen as tuberculosis group ,20 cases of patiente with lung cancer pleural effusion as malignant group and 30 cases of patiente with hepatic hydrothorax as control group .The concentrations of CysC and ADA in the pleural effusion and serum were detected ,and the ratios of these two indexes in the pleural effusion and serum were calculated .Re-sults (1)The results in three groups including PADA and SADA ,SCysC and PCysC ,PCysC/SCysC and PADA/SADA were com-pared ,and the differences were statistically significant (P<0 .05) .(2) According to the ROC curve ,the critical value of PADA/SA-DA and PCysC/SCysC were set as 1 .58 and 2 .30 ,respectively ,and area under the curve of PADA/SADA and PCysC/SCysC were 0 .880 and 0 .786 respectively .Conclusion The diagnostic value of PADA/SADA and PCysC/SCys for tuberculous pleural effusion is higher than that of PADA ,SADA ,PCysC or SCysC alone ,which can be used for the differential diagnosis of tuberculous pleural effusion index for clinical application .
