Advances in treatment of muscle cramp in liver cirrhosis
10.3969/j.issn.1001-5256.2017.10.033
- VernacularTitle:肝硬化肌肉痉挛的治疗进展
- Author:
Wenshan ZHAO
1
;
Hong YOU
;
Xinyan ZHAO
Author Information
1. 首都医科大学附属北京友谊医院肝病中心
- Keywords:
liver cirrhosis;
muscle cramps;
therapy;
review
- From:
Journal of Clinical Hepatology
2017;33(10):2001-2003
- CountryChina
- Language:Chinese
-
Abstract:
Muscle cramp is one of the common symptoms of patients with liver cirrhosis and significantly affects patients' quality of life.In general,the research on liver cirrhosis mainly focuses on the management and prevention of causes or common complications,and there are relatively few studies on the treatment of muscle cramp.Therefore,it is very important to find safe and effective therapeutic regimens.This article describes the pathogenesis and manifestations of muscle cramp in patients with liver cirrhosis,summarizes the therapeutic regimens with clinical value,including new drugs such as baclofen,L-carnitine,and taurine,and further elaborates on the protective effect of taurine against liver fibrosis via its activation of extracellular matrix and hepatic stellate cells,in order to provide new evidence for the treatment of muscle cramp in liver cirrhosis.
