Research progress on intestinal tract microorganisms in zebrafish
10.3969/j.issn.1005-4847.2017.06.009
- VernacularTitle:斑马鱼肠道微生物的研究进展
- Author:
hua Jin ZHANG
1
;
Fang GUI
;
Jing SI
;
Hong ZHANG
;
Rong ZHOU
;
Lu GAN
Author Information
1. 中国科学院近代物理研究所
- Keywords:
Intestinal microbiota;
Zebrafish;
Related function;
Succession rule;
Influencing factors;
Human health
- From:
Acta Laboratorium Animalis Scientia Sinica
2017;25(6):637-642
- CountryChina
- Language:Chinese
-
Abstract:
Intestinal microbiota as an important "microbial organ" in the human body may play a key role in the human development, intestinal barrier, immune regulation, digestion and nutrient absorption, detoxification, angiogenesis, as well as the occurrence and development of diseases. As a vertebrate biotype, zebrafish is widely used in the fields of de-velopmental biology, immunology, genetics, toxicology and the establishment of human disease models, because of their common development and phylogenetic system with humans. A number of unique features, including its transparent embry?os, rapid development, easy to take intestinal samples, and other advantages, made its wide popularity as an ideal model for the study of intestinal microbes. However, the research on zebrafish intestinal microbiology is still at an elementary stage. This paper summarizes the recent progress in research of zebrafish intestinal microbiota, including the related func?tion of intestinal microbes in zebrafish, the assembly and succession of intestinal microbial community and factors influen?cing the intestinal microbial structure, and provides a theoretical basis for studying the effects of intestinal microbes on hu?man health and its application in the treatment of diseases.
