Study on the Fingerprints of the Best Anti-MDR-MRSA Components in the Combination of Honeysuckle and Forsythia
- VernacularTitle:金银花、连翘配伍抗MDR-MRSA最佳活性组分的指纹图谱研究
- Author:
Yujie LIU
1
;
Changfu WANG
;
Yan QI
;
Boyu JIA
Author Information
1. 黑龙江中医药大学 哈尔滨150040
- Keywords:
Honeysuckle;
Forsythia;
MDR-MRSA;
The best active ingredients;
Fingerprints
- From:
China Pharmacist
2017;20(12):2110-2111,2152
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To establish the fingerprints of the best anti-MDR-MRSA components in the combination of honeysuckle and forsythia. Methods:The best active anti-MDR-MRSA ingredients of honeysuckle and forsythia were dissolved in 10% methanol water. A Waters Atlantis T3 (250 mm × 4. 6 mm, 5 μm) column was eluted with water and methanol as the mobile phase. The optimal chro-matographic conditions were determined by optimizing the mobile phase and chromatographic conditions. The fingerprints similarity of 10 batches of active anti-MDR-MRSA components in honeysuckle and forsythia was studied. Results:The best active ingredients of the combination of honeysuckle and forsythia showed 7 peaks with promising separation. The similarity of the 10 samples was greater than 0. 9. Conclusion:The fingerprints of the best active anti-MDR-MRSA ingredient in the combination of honeysuckle and forsythia are stable, and can be used for the quality evaluation of the components.
