Study on Processing Technology of Alum by Central Composite Design and Response Surface Method
- VernacularTitle:白矾星点设计-效应面法炮制工艺研究
- Author:
Wei LI
1
;
Ruihai LI
Author Information
1. 辽宁中医药大学药学院 辽宁大连116600
- Keywords:
Alum;
Central composite design and response surface method;
Oven;
Processing technology
- From:
China Pharmacist
2017;20(12):2135-2138
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To optimize the processing technology of alum by using oven processing combined with central composite design and response surface method to provide basis for processing standardization production of alum. Methods:Alum as the raw ma-terial and on the basis of single factor experiment, the processing temperature, processing time and alum amount were used as the three independent variables factors. A titration method was applied in the content determination of aluminium potassium sulfate in withered alum, and a central composite design and response surface method was used to optimize the processing technology of alum. Results:The optimal processing technology of alum was as follows:the processing temperature was 250℃ with 40-minute processing time and 8 g alum. Conclusion:The optimized alum processing technology by central composite design and response surface method is simple, stable and predictable, which can provide basis for the processing standardization production of alum.
